What drives aging?

How Aging Research Is Changing Our Lives

Biologist Eric Verdin considers aging a disease. His research group famously discovered several enzymes, including sirtuins, that play an important role in how our mitochondria—the powerhouses of our cells—age. His studies in mice have shown that the stress caused by calorie restriction activates sirtuins, increasing mitochondrial activity and slowing aging. In other words, in the lab, calorie restriction in mice allows them to live longer. His work has inspired many mitochondrial hacks—diets, supplements, and episodic fasting plans—but there is not yet evidence that these findings translate to humans. ….[READ]

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